Magnesium: The Disregarded Cation

Can Nonenhancing White Matter Lesions Be Disregarded?

In this issue of AJNR (1), Drs Elster and Chen pose a provocative question that has certainly given us pause as we routinely dismiss a large nonenhancing white matter lesion in a cancer patient. It was with relief that we read the conclusion that white matter lesions in cancer patients that do not enhance with gadolinium-DTPA at the time of the initial MR study have a low probability of represe...

Learning-Disabled Children: A Disregarded User Group

In usability research it is a common practice to take young and healthy university students as participants for usability evaluations. This chapter focuses on the “weaker” mobile phone users, which have been mostly disregarded in this field: Learning-disabled children. Their interaction with mobile phones is compared to that of average children and students. Results show that the consideration ...

ATP and PIP2 dependence of the magnesium-inhibited, TRPM7-like cation channel in cardiac myocytes.

The Mg(2+)-inhibited cation (MIC) current (I(MIC)) in cardiac myocytes biophysically resembles currents of heterologously expressed transient receptor potential (TRP) channels, particularly TRPM6 and TRPM7, known to be important in Mg(2+) homeostasis. To understand the regulation of MIC channels in cardiac cells, we used the whole cell voltage-clamp technique to investigate the role of intracel...

Cryptosporidiosis – an occupational risk and a disregarded disease in Estonia

BACKGROUND Cases of cryptosporidiosis have not been officially reported in Estonia after the year 2000, and the disease appears to be either under-diagnosed or under-reported. FINDINGS Based on a human case of cryptosporidiosis contracted during faecal sampling in dairy farms, cattle considered to be sources of infection were analysed for Cryptosporidium spp. by a modified Ziehl Neelsen techn...

Dirty-appearing white matter: a disregarded entity in multiple sclerosis.